by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeBleacherBreaker4 Sisters Take The Same Picture For 40 Years. Don’t Cry When You See The Last One!BleacherBreakerDaily FunnyFemale Athlete Fails You Can’t Look Away FromDaily Funnybonvoyaged.comTotal Jerks: These Stars Are Horrible People.bonvoyaged.comNoteableyAirport Security Couldn’t Believe These Jaw-Dropping MomentsNoteableyzenherald.comMeghan Markle Changed This Major Detail On Archies Birth Certificatezenherald.comMisterStoryWoman Files For Divorce After Seeing This Photo – Can You See Why?MisterStoryNinjaJournalistThe Most Expensive Royal Weddings In Royals HistoryNinjaJournalistArticles StoneTeacher Throws Marine Out, He Gets The Last LaughArticles StoneZen HeraldEllen Got A Little Too Personal With Blake Shelton, So He Said ThisZen Herald The zero growth figure was below analysts’ expectations of a 0.2 per cent expansion, and shows that the pick-up in confidence after Prime Minister Boris Johnson’s December election win failed to translate into higher output. Harry Robertson UK economy posted zero growth even before coronavirus (AFP via Getty Images) Also Read: UK economy posted zero growth even before coronavirus Chancellor Rishi Sunak is today set to unveil a number of spending measures to tackle coronavirus when he gives the first Budget since the election. He told the BBC on Sunday that the NHS would get “whatever resources it needs”. whatsapp Wednesday 11 March 2020 9:57 am “The dominant service sector also showed no growth in the latest three months with falls in retail and telecoms balanced by strength in rentals, employment and education.” The Bank of England today slashed interest rates after an emergency meeting in an effort to boost confidence and encourage lending in the economy. The cut took the interest rate back to 0.25 per cent, its lowest-ever level. whatsapp The UK economy flatlined in January, data has shown, as industrial production contracted and the services sector struggled even before coronavirus spread in Britain. Threadneedle Street’s monetary policy committee (MPC) said: “Temporary, but significant, disruptions to supply chains and weaker activity could challenge cash flows and increase demand for short-term credit from households and for working capital from companies.” In the three months to January the UK economy also registered zero growth as the country’s giant services sector stagnated, the Office for National Statistics (ONS) said. ONS head of GDP Rob Kent-Smith said that in the three months to January, “growth in construction, driven by housebuilding, offset yet another decline in manufacturing, particularly the drinks, cars and machinery industries”. (AFP via Getty Images) Also Read: UK economy posted zero growth even before coronavirus Share The Office for Budget Responsibility (OBR) will today release updated forecasts for the UK economy, although the spread of coronavirus could quickly make them out of date. (AFP via Getty Images) Deutsche Bank has said it expects UK GDP to grow by just 0.5 per cent this year due to coronavirus. The zero growth figure for January heightens the chances of a recession – two quarters of contracting output – in the first half the year. The worse-than-expected GDP reading suggests that the UK economy could be hit harder by coronavirus than initially thought. There have now been 382 infections and six deaths from the virus in the UK. The outbreak threatens the economy as people quarantine themselves, offices and factories close, and supply chains around the world are disrupted. Show Comments ▼
Family | Federal Government | Sexual Abuse & Domestic Violence | SouthwestDomestic violence shelters face ‘terrible choices’ from looming federal cutsApril 8, 2021 by Greg Kim, KYUK – Bethel Share:Bethel’s annual Peace Walk, hosted by the Tundra Women’s Coalition, on Oct. 3, 2016. (Credit Katie Basile / KYUK)Domestic violence shelters around the nation are preparing for a large decrease in federal funding that will take effect in a few months. Tundra Women’s Coalition in Bethel said that it will mean a 20% cut in its operating budget and could lead to a significant loss in services.Federal funding for domestic violence and women’s shelters from the Victims of Crimes Act has been decreasing in recent years. The Council on Domestic Violence and Sexual Assault is an organization within the Alaska Department of Public Safety that directs federal funding to victim services programs within the state.In a letter sent on April 1, CDVSA Executive Director Diane Casto wrote that Victims of Crimes Act funding would decrease by 34.6% from the previous year. This would affect shelters like Tundra Women’s Coalition and the Emmonak Women’s Shelter in Fiscal Year 2022, which begins in July.“Everyone was like ‘what is everybody going to do? What are the shelter programs going to do?’ It was devastating news,” said JoAnn Horn, director of Emmonak Women’s Shelter.Bethel’s Tundra Women’s Coalition Executive Director Eileen Arnold explained how that decrease in federal funding would affect her organization’s bottom line.“It’s like 20% of our full, annual operating budget. It’s deep, it’s significant,” Arnold said.She said with that large of a funding cut, TWC will have to think about eliminating services.“That amount of money would equal, like, the entire Children’s Advocacy Center, or it would be the entire shelter,” Arnold said. “These are terrible choices.”Arnold said that TWC could also consider cutting part of every program.“But that’s just as difficult because our staff are already under-resourced and overwhelmed with work,” Arnold said.Horn said that if they can’t find more money, the Emmonak Women’s Shelter would likely have to cut the number of its advocates. Advocates answer crisis calls 24 hours a day for the 13 villages that Emmonak Women’s Shelter serves. They also arrange accommodations for women and children at the shelter and coordinate with law enforcement.Arnold is hoping that the state can help fill the budget gap left by the decrease in federal funding. Arnold is asking people to call their state legislators to advocate on behalf of their shelters.“I hope that TWC has helped people in this community. And for the people that it has helped, I hope that they would tell our legislators that,” Arnold said.There is a House Finance Committee hearing on Friday, April 9 at 1:30 p.m. to share public testimony on the state’s operating budget.Share this story:
By Mike Wackett in Busan 14/10/2016 Busan © Sean Pavone Hanjin Shipping has received bankruptcy court approval to sell assets, including its largest trade route, between Asia and North America.It is the latest development in the embarrassing demise of the South Korean carrier that has left the nation in shock and the country’s largest port at Busan with a potential huge loss of box throughput.However Busan Port Authority contacts told The Loadstar they are optimistic there won’t be an appreciable loss of throughput, as other carriers have quickly stepped in to fill the void.But other sources said rates from Busan had risen significantly as a consequence.A spokesman for the Seoul Central District Court said yesterday the carrier’s assets would be sold to meet creditors’ claims. These are being collated and must be submitted by 25 October.According to its court filing, Hanjin had debts of $5.4bn at the end of June, but this seems likely to have increased after costs associated with charter party and container lease contract defaults are added.Shipowners face significant costs for the return of their ships, while unpaid bunker fuel bills will be substantial, as could lessor claims for repositioning equipment.Many other service providers remain unpaid and legal costs to protect the interests of creditors could add a third to the debt, according to one shipping lawyer.Hanjin will receive letters of intent concerning the assets sale by 28 October, but declined to comment on asking prices or interested parties.The court spokesman said the potential sale would include manpower systems, five containerships and 10 overseas businesses.When Hanjin entered receivership the carrier had an 8.4% market share of the transpacific tradelane and 17.8% of the South Korea to US route, with companies such as LG and Samsung shipping sending 20% and 40% respectively of their exports with the carrier.However, it could be argued that Hanjin does not have much of value to sell, other than its port investments.Tradelane market share has now been taken by other carriers, including compatriot Hyundai Merchant Marine (HMM), which launched an additional service to target Hanjin shippers.And there is no “good will” to sell after the carrier “abandoned customers” by seeking court protection from creditors, and its manpower systems might also be of little value after the line’s failure.Details of the five containerships involved have not been disclosed, but if they are panamaxes their value might be limited to scrap.There are no details of the “10 overseas businesses”, but it is assumed that they are regional offices in the US, and their value would depend on whether they are owned or leased.Like many container terminals around the world, Busan and Hanjin’s local, Newport, have stack after stack of blue Hanjin containers awaiting retrieval.But one container leasing surveyor in Busan told The Loadstar some container owners may decide to abandon empty equipment if the cost of restitution and depot or terminal pickup charges were higher than 75% of the book value of the box.
Submissions are open until 3 p.m. on Oct. 31.Click here to submit your photo.By submitting this form you indicate that you own the copyright of the photos and you agree to allow STAT to use submitted images and text on its website and on social channels. Tags halloween Jason Redmond/AFP/Getty Images STAT staff Your ThoughtsWhat are you going to be for Halloween? Share your science selfie! By STAT staff Oct. 27, 2017 Reprints About the Author Reprints [email protected] Is your Halloween costume inspired by science? Motivated by medicine?Let’s see!Fill out the form by clicking the link below, or share your photos on Facebook, Twitter or Instagram using the hashtag #SpookyScience and you could be featured in a Halloween story.advertisement
Laois County Council team up with top chef for online demonstration on tips for reducing food waste Laois County Council create ‘bigger and better’ disability parking spaces to replace ones occupied for outdoor dining By Sean Hennessy – 19th March 2018 Council Pinterest This week’s My Farming Life interview is with Helen Dempsey, a young woman who balances her time farming, teaching and a very strong involvement with Macra na Feirme.Although just across the border in Cloneyhurke, she is chairperson of Laois Macra and treasurer of the Mountmellick club.What type of farm do you have?We have a Bull Beef Enterprise. We rear calves from 10-12 weeks to finish.What made you take the path of farming?It was a natural progression really. My Mother was brought up on a farm in Kilcolman, Co. Offaly and we live on my Dad’s home farm. I’ve been involved from a young age. I always thought my older brother, Liam would get the farm but when he moved to Dublin for work I became much more involved.We sat down as a family and had a discussion about a 3 way partnership between Daddy, Liam and I; with a view to succession. We’re in the early stages of setting this plan in motion.Where did you acquire your farming knowledge?First and foremost, at home getting hands on experience working alongside my parents and brothers. Then through my involvement in Macra na Feirme – taking part in agricultural competitions, upskilling through Skillsnet courses and engaging with local farm walks (through Macra or IFA). I’m will be applying to do the Green Cert when applications open next.Have you got a degree or qualification outside of farming, or if not, what would you like to do if you were not a farmer?Yes, I have a Bachelor of Business Studies with French from University of Limerick and a Higher Diploma in Primary Education from Hibernia College. I currently work in Rathangan Boys National School as a Learning Support Teacher.What is your favourite aspect of farming?I love getting outside for fresh air and the chance to spend time working alongside Daddy. There’s also a certain satisfaction from finishing a project you’ve had in the pipeline for some time.What is your least favourite aspect of farming?How unpredictable animals can be – and after the recent weather I’m not a huge fan of farming in the snow either!Do you think farming is sustainable as a full-time job, or do you think farmers need an outside income to keep going forward?In some areas, depending on a farms resources – absolutely. We have quite a small enterprise, and the farm income is supplemented. Daddy is self-employed and constructs sheds in the Laois-Offaly-Westmeath area.As Liam and I both have careers outside the farming industry, our plan in the future is to hire a full-time farm manager once we expand the farm. In the next 5 years we’re looking at doubling our herd, we plan on increasing our housing capacity and to install a slated tank.What is your daily routine on the farm?I’m lucky, as Daddy does the jobs in the morning because I’m heading to school. In the evenings, I will try and have the calves/bulls fed before Daddy gets home, and during the summer I’ll check on the herd if they’re out in different fields.What time of the year are you most busy on the farm and why?We finish off the bulls in 2 stages. One half is brought in in September and finished in May and the other half is brought in in May and finished in January.They’re on a diet of silage, hay and 1kg of meal per head over summer (which is thrown in by hand!). We presently only take one cut of silage (about 200 bales) but with our plan to expand we will have to increase our volume of silage.What is your favourite time of the year on the farm?Summer time – bulls are out to grass, longer evenings and usually better weather!What does Macra na Feirme do in the farming community and what role do you play in the organisation?I’m in my second term as Chairperson of Laois Macra na Feirme. Mountmellick Macra is my home club and I’m Treasurer of the club. I also sit on the National Competitions Committee which involves working as part of a team to help roll out the jam packed competitions calendar which Macra offers its members.My role is to represent and lead our membership. We have eight clubs across the county and almost 300 members. Farming can be a very isolating profession, especially in rural Ireland that Macra na Feirme acts as a lifeline for local communities.Macra educates the future leaders of the farming industry, it brings likeminded young people together and it keeps rural Ireland relevant in Ireland today.Why is it important to have young people entering the farming and agriculture sector?Farming is an aging profession and to keep it alive you need new blood in the profession. Farming has progressed and advanced so much in recent years, young people are not afraid to try and make the most of modern farming practices and technologies.What more can be done to encourage young people to choose farming as a path in life?The value of the grants offered is diminished by the expense of carrying out building work to a higher spec (Industrial Standard) than might be needed – this is an area that could be looked at.Final question, if you had one piece of advice for young person who was thinking of choosing a career in farming what would it be?Be ambitious but always have farm safety to the fore of your mind – and I wouldn’t be doing my job if I didn’t say join Macra!It’s a great outlet for a social life, it’s good for your mental health as you’re meeting new people, trying new things and getting active in your local community!SEE ALSO – Massive increase in the price paid for farming land in Laois in 2017 Previous articleHere are all of this week’s Laois GAA fixturesNext articleIn Pictures: Laois school help launch dog fouling awareness campaign Sean HennessyA former Knockbeg student, and is currently a student in the University of Limerick trying to scrape a BA in History and Politics. A marquee player in the goals for Annanough, but well capable of doing a job in full-forward and has the knack to turn his hand to any sport (except running). Only starting out in his journalistic career but already the specialist farming and property reporter. Happiest when Liverpool and Laois are winning! Rugby My Farming Life: Meet the woman steeped in the Macra, Teaching and farming Facebook Twitter Facebook Twitter RELATED ARTICLESMORE FROM AUTHOR Community Home We Are Laois My Farming Life My Farming Life: Meet the woman steeped in the Macra, Teaching and… We Are LaoisMy Farming Life Pinterest WhatsApp WhatsApp TAGSfarmingHelen DempseyLaois Macra na FeirmeMy Farming Life Ten Laois based players named on Leinster rugby U-18 girls squad
Another Sydney Metro milestone reached The NSW Government has approved a landmark building above the future Pitt Street Sydney Metro station in another milestone for Australia’s largest public transport project.Minister for Planning and Public Spaces Rob Stokes said the 39-storey Pitt Street North commercial office tower will be integrated with the station to creating a connected hub of offices, shops and world-class public transport.“This approval means up to 620 construction jobs and 4,000 operational jobs once the building is complete which is great news for NSW as we continue to recover from the pandemic,” Mr Stokes said.“The Pitt Street North development will provide nearly 55,000 square metres of commercial and retail space, creatingnew places for office workers, commuters, visitors and CBD residents.“As life starts to return to normal, we want to create new and exciting places to draw people back into the CBD whilst boosting the economy at the same time.”Minister for Transport Andrew Constance said the construction of Metro stations in Sydney provides opportunities to create new hubs and precincts.“The Sydney Metro City and South-west mega project is not only changing the city below ground, it’s transforming the city skyline,” Mr Constance said.“We will soon have 31 stations and 66 kilometres of new metro rail moving people all the way from Rouse Hill to Bankstown, via Sydney CBD. At the same time it’s unlocking the city’s potential on the global scale and opening up new opportunities.” /Public Release. This material comes from the originating organization and may be of a point-in-time nature, edited for clarity, style and length. View in full here. Why?Well, unlike many news organisations, we have no sponsors, no corporate or ideological interests. We don’t put up a paywall – we believe in free access to information of public interest. Media ownership in Australia is one of the most concentrated in the world (Learn more). Since the trend of consolidation is and has historically been upward, fewer and fewer individuals or organizations control increasing shares of the mass media in our country. According to independent assessment, about 98% of the media sector is held by three conglomerates. This tendency is not only totally unacceptable, but also to a degree frightening). Learn more hereWe endeavour to provide the community with real-time access to true unfiltered news firsthand from primary sources. It is a bumpy road with all sorties of difficulties. We can only achieve this goal together. Our website is open to any citizen journalists and organizations who want to contribute, publish high-quality insights or send media releases to improve public access to impartial information. You and we have the right to know, learn, read, hear what and how we deem appropriate.Your support is greatly appreciated. All donations are kept completely private and confidential.Thank you in advance!Tags:Australia, Bankstown, building, Economy, environment, future, Government, Minister, New South Wales, NSW, pandemic, planning, project, public transport, space, Sydney, Sydney Metro, Transport
Immigration: Complexities and Challenges Regardless of who’s in charge, immigration and the U.S. government’s approach to it is a thorny topic. Researchers across Duke are informing the debates with factual data on why and how people immigrate to the U.S., what happens after they arrive and how immigration affects everyone involved.HOW VIOLENCE AND CLIMATE CHANGE ARE DRIVING MIGRATIONLong-term solutions to the increasing number of migrants crossing the U.S. border with Mexico requires research into what drives migration.Sarah Bermeo, director of graduate studies at the Duke Center for International Development, found immigration from Honduras – which jumped sharply in 2019 after years of steady increase – has resulted from persistent violence coupled with sharp increases in food insecurity linked to climate change.Full StoryWHAT HAPPENS WHEN MIGRANTS ARE SENT BACKScholars know little about what happens to people once they’re deported from the U.S., including whether they plan to return to the United States.Political science Professor Erik Wibbels was one of a group of political scientists who studied the fates of immigrants deported to Guatemala, which receives the most U.S. deportees after Mexico.Full StoryDEPORTATION OVER MINOR CRIMESIn March, a divided U.S. Supreme Court ruled in a case involving whether an immigrant living in the country without authorization can seek relief from deportation for a minor crime.Kate Evans, a clinical law professor who directs the Immigration Law Clinic at Duke Law School, explains how the ruling could have strict consequences for some non-citizens seeking deportation relief.Full StoryCROSSING THE DARIEN GAPFor most U.S.-bound migrants crossing the Colombian border with Panama, the only option is to find clandestine routes through the Darien Gap, an unforgiving jungle where they are left without guides, with little or no food to find along the way, and under the constant threat of robbery.Piotr Plewa, a visiting research scholar at Duke who specializes in international migration, explains what migration trends through the Darien Gap mean for the region.Full StoryTHE U.S./MEXICO RELATIONSHIP: COMPLEX, CHALLENGING AND UNIQUE As Mexican Ambassador to the U.S., one of Martha Bárcena Coqui’s biggest challenges is to make the American public understand how their own future is directly linked to Mexico and its people.Coqui shared with a Duke audience how in the last 30 years, the two countries have gone from distant neighbors to essential partners.Full Story /Public Release. This material comes from the originating organization and may be of a point-in-time nature, edited for clarity, style and length. View in full here. Why?Well, unlike many news organisations, we have no sponsors, no corporate or ideological interests. We don’t put up a paywall – we believe in free access to information of public interest. Media ownership in Australia is one of the most concentrated in the world (Learn more). Since the trend of consolidation is and has historically been upward, fewer and fewer individuals or organizations control increasing shares of the mass media in our country. According to independent assessment, about 98% of the media sector is held by three conglomerates. This tendency is not only totally unacceptable, but also to a degree frightening). Learn more hereWe endeavour to provide the community with real-time access to true unfiltered news firsthand from primary sources. It is a bumpy road with all sorties of difficulties. We can only achieve this goal together. Our website is open to any citizen journalists and organizations who want to contribute, publish high-quality insights or send media releases to improve public access to impartial information. You and we have the right to know, learn, read, hear what and how we deem appropriate.Your support is greatly appreciated. All donations are kept completely private and confidential.Thank you in advance!Tags:Ambassador, american, climate change, deportation, Duke University, gap, Government, Guatemala, Honduras, immigrants, immigration, Mexican, Mexico, Panama, Scientists, Supreme Court, United States, university
On road to recovery with help from specialised staff The economic and social impacts of the pandemic are immense across the Mornington Peninsula. At the peak of the downturn in August last year, 2,205 local jobs were lost and pre-existing social and health issues worsened.Local governments play an important role in ensuring the health and wellbeing of their communities. We are working to reconnect our communities, build economic resilience, revitalise our cultural, creative and recreation industries and reactivate our Peninsula.As part of our plan for recovery, we are taking part in Working for Victoria, the Victorian Government’s $500 million initiative helping Victorian jobseekers find work and employers find workers. We have secured State Government funding for 41 new employees on a temporary basis throughout 2021. The roles contribute directly or indirectly to our community’s recovery, including in areas of volunteering, community houses, business liaison, health and wellbeing, events, seniors inclusion, township activation, community engagement, youth employment and creative industries.Every effort has been made to ensure resources are allocated directly to assist areas greatly impacted by the pandemic:A Creative Sustainability Officer will help breathe new life into our creative industry by connecting our artists to spaces and encouraging community to participate in events, after school classes, exhibitions and more. Professional development workshops will be offered to artists and organisations, as well as one on one support to those most in need.Many experienced mental wellbeing issues and lower levels of life satisfaction during lockdown. Assisting our residents through health and wellbeing initiatives will be a key focus of the Health and Wellbeing Officer as they work in partnership with relevant providers to implement evidence based preventative approaches. A Senior Inclusions Officer will support local organisations, groups and networks aiming to engage older people including U3As and senior citizens groups, support the delivery of the Positive Ageing Strategy and approaches aimed at increasing community capacity and empowerment as well as share positive ageing messages, initiatives and campaigns. /Public Release. This material comes from the originating organization and may be of a point-in-time nature, edited for clarity, style and length. View in full here. Why?Well, unlike many news organisations, we have no sponsors, no corporate or ideological interests. We don’t put up a paywall – we believe in free access to information of public interest. Media ownership in Australia is one of the most concentrated in the world (Learn more). Since the trend of consolidation is and has historically been upward, fewer and fewer individuals or organizations control increasing shares of the mass media in our country. According to independent assessment, about 98% of the media sector is held by three conglomerates. This tendency is not only totally unacceptable, but also to a degree frightening). Learn more hereWe endeavour to provide the community with real-time access to true unfiltered news firsthand from primary sources. It is a bumpy road with all sorties of difficulties. We can only achieve this goal together. Our website is open to any citizen journalists and organizations who want to contribute, publish high-quality insights or send media releases to improve public access to impartial information. You and we have the right to know, learn, read, hear what and how we deem appropriate.Your support is greatly appreciated. All donations are kept completely private and confidential.Thank you in advance!Tags:community engagement, Employees, employment, empowerment, Government, health, local council, mental wellbeing, Mornington Peninsula, older people, professional development, resilience, resources, social impact, sustainability, Victoria, wellbeing
Share Share via TwitterShare via FacebookShare via LinkedInShare via E-mail Published: April 22, 2003 University of Colorado at Boulder student Corry L. Lee has been named a 2003 Goldwater Scholar by the Barry M. Goldwater Scholarship and Excellence in Education Foundation. The Goldwater scholarship is a prestigious national competition for undergraduates in the fields of mathematics, science and engineering. The scholarship funds up to $7,500 per year for approximately 300 sophomores and juniors from across the country to complete their undergraduate degrees. This year’s scholars were selected on the basis of academic merit from a field of 1,093 students nominated by the faculties of colleges and universities nationwide. Another CU-Boulder student, Sharon Lutz, received an honorable mention in this year’s competition. “We’re pleased to have such high-achieving students here at CU-Boulder,” said Lori Goodman, who coordinates top national scholarships for the campus. “We tend to do very well in this competition, which is a sign of the national prominence held by our programs in math, science and engineering.” Lee is a junior majoring in applied mathematics and engineering physics. She has conducted undergraduate research in particle physics, both through the physics department at CU-Boulder and at the European Organization for Nuclear Research in Switzerland. She is writing an honors thesis in particle physics and contributing to a research paper in applied mathematics. Candidates are expected to have one or two significant research experiences along with a stated goal of pursuing a doctoral degree and working in research after they complete their studies. “Corry is an outstanding student who has taken advantage of, and excelled at, some of the many opportunities afforded to CU students. I am confident we will be hearing more about her successes in the future,” said Anne Dougherty, associate chair of applied mathematics and faculty representative to CU-Boulder’s Goldwater Scholars program. The Barry M. Goldwater Scholarship and Excellence in Education Foundation is a federally endowed agency established by Congress in 1986 to encourage and assist outstanding students to pursue careers in the fields of mathematics, natural sciences and engineering. The program honors the late Sen. Barry Goldwater, who served the United States for 56 years as a soldier and statesman, including 30 years in the U.S. Senate.
News Purdue researchers create device to identify risks for breast cancer MaxiVision Eye Hospitals launches “Mucormycosis Early Detection Centre” Read Article Menopause to become the next game-changer in global femtech solutions industry by 2025 Share The missing informal workers in India’s vaccine story Related Posts The device is a small plastic case with several thin layers and an opening for a piece of paper where researchers can place a portion of tissueResearchers at Purdue University are creating a device that they hope will help identify risk factors that cause breast cancer.The device, known as risk-on-a-chip, is a small plastic case with several thin layers and an opening for a piece of paper where researchers can place a portion of tissue. This tiny environment produces risk factors for cancer and mimics what happens in a living organism.“We want to be able to understand how cancer starts so that we can prevent it,” said Sophie Lelièvre, Professor of Cancer Pharmacology, Purdue.The key to preventing cancer is understanding how it starts, but people generally don’t want to be prodded with potential carcinogens. Cancer is a disease of gene expression, and organisation of genes is specific to a particular species and organ, which means it wouldn’t be useful to perform this study on rats or mice. Thus, Lelièvre needs a model that will mimic the organ in question. She teamed up with Babak Ziaie, a professor of electrical and computer engineering at Purdue, to create the device.“Unlike conventional 2-D monolayer cell culture platforms, ours provides a 3-D cell culture environment with engineered gradient generators that promote the biological relevance of the environment to real tissue in the body,” said Rahim Rahimi, a graduate student in Ziaie’s lab.The risk-on-a-chip is based on an earlier cell culture device developed by Lelièvre and Ziaie to study cancer progression. To modify it for prevention, Ziaie plans to add nanosensors that measure two risk factors: oxidative stress and tissue stiffness.Oxidative stress is a chemical reaction that occurs as the result of diet, alcohol consumption, smoking or other stressors, and it alters the genome of the breast, aiding cancer development. The risk-on-a-chip will simulate oxidative stress by producing those molecules in a cell culture system that mimics the breast ducts where cancer starts.Tissue stiffness refers to the stiffness of breast tissue, which has been found to contribute to onset and progression of breast cancer. The research team will measure stiffness within a tunable matrix made of fibres, whose density is relative to stiffness.Breast cancer is particularly difficult to prevent because multiple risk factors work independently or in combination to promote disease onset. To account for this, the risk-on-a-chip will be tailorable to different groups of women at risk.“We need to see if there’s a difference in primary cells from black women or Asian women or white women, because that matters,” Lelièvre said. “The way our genome is organised depends on an individual’s ancestry and lifestyle; it’s very complex. That’s why cancer is so difficult to treat.”The research team believes the risk-on-a-chip could be used to study additional risks by adding more cell types and biosensors. They estimate that optimisation for each new condition will take between six months and a year.Lelièvre and Ziaie have received a joint grant from the Department of Defense (W81XWH-17-1-0250) to create and test the device with structures that mimic the mammary gland, which will provide more than $500,000 over the next two years.This project is part of the international breast cancer and nutrition collaboration. Indraprastha Apollo Hospitals releases first “Comprehensive Textbook of COVID-19” Phoenix Business Consulting invests in telehealth platform Healpha By salil sule on September 15, 2017 Heartfulness group of organisations launches ‘Healthcare by Heartfulness’ COVID care app WHO tri-regional policy dialogue seeks solutions to challenges facing international mobility of health professionals